A comprehensive survey of C. elegans argonaute proteins reveals organism-wide gene regulatory networks and functions

A comprehensive survey of C. elegans argonaute proteins reveals organism-wide gene regulatory networks and functions

Argonaute (AGO) proteins associate with small RNAs to direct their effector function on complementary transcripts. The nematode Caenorhabditis elegans contains an expanded family of 19 functional AGO proteins, many of which have not been fully characterized. In this work, we systematically analyzed...

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Bibliographic Details
Main Authors: Uri Seroussi, Andrew Lugowski, Lina Wadi, Robert X Lao, Alexandra R Willis, Winnie Zhao, Adam E Sundby, Amanda G Charlesworth, Aaron W Reinke, Julie M Claycomb
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2023-02-01
Series:eLife
Subjects:
Argonaute
miRNA
piRNA
22G-RNA
26G-RNA
gene regulation
Online Access:https://elifesciences.org/articles/83853

Internet

https://elifesciences.org/articles/83853

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