Aspergillus fumigatus cytochrome c impacts conidial survival during sterilizing immunity

ABSTRACTInvasive pulmonary aspergillosis (IPA) is a life-threatening infection caused by species in the ubiquitous fungal genus Aspergillus. While leukocyte-generated reactive oxygen species (ROS) are critical for the clearance of fungal conidia from the lung and resistance to IPA, the processes tha...

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Bibliographic Details
Main Authors: Matthew R. James, Mariano A. Aufiero, Elisa M. Vesely, Sourabh Dhingra, Ko-Wei Liu, Tobias M. Hohl, Robert A. Cramer
Format: Article
Language:English
Published: American Society for Microbiology 2023-12-01
Series:mSphere
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/msphere.00305-23