SDHi fungicides: An example of mitotoxic pesticides targeting the succinate dehydrogenase complex

SDHi fungicides: An example of mitotoxic pesticides targeting the succinate dehydrogenase complex

Succinate dehydrogenase inhibitors (SDHi) are fungicides used to control the proliferation of pathogenic fungi in crops. Their mode of action is based on blocking the activity of succinate dehydrogenase (SDH), a universal enzyme expressed by all species harboring mitochondria. The SDH is involved in...

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Bibliographic Details
Main Authors: Carolina Duarte Hospital, Arnaud Tête, Kloé Debizet, Jules Imler, Céline Tomkiewicz-Raulet, Etienne B. Blanc, Robert Barouki, Xavier Coumoul, Sylvie Bortoli
Format: Article
Language:English
Published: Elsevier 2023-10-01
Series:Environment International
Subjects:
Pesticides
Mitochondria
Cancer
Oncometabolite
Mitotoxicity
Online Access:http://www.sciencedirect.com/science/article/pii/S0160412023004920

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http://www.sciencedirect.com/science/article/pii/S0160412023004920

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