CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques

CMV Primes Functional Alternative Signaling in Adaptive Δg NK Cells but Is Subverted by Lentivirus Infection in Rhesus Macaques

Summary: Despite burgeoning evidence demonstrating the adaptive properties of natural killer (NK) cells, mechanistic data explaining these phenomena are lacking. Following antibody sensitization, NK cells lacking the Fc receptor (FcR) signaling chain (Δg) acquire adaptive features, including robust...

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Bibliographic Details
Main Authors: Spandan V. Shah, Cordelia Manickam, Daniel R. Ram, Kyle Kroll, Hannah Itell, Sallie R. Permar, Dan H. Barouch, Nichole R. Klatt, R. Keith Reeves
Format: Article
Language:English
Published: Elsevier 2018-12-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124718317662

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http://www.sciencedirect.com/science/article/pii/S2211124718317662

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