Identification and characterization of a heme exporter from the MRP family in Drosophila melanogaster

Abstract Background The heme group constitutes a major functional form of iron, which plays vital roles in various biological processes including oxygen transport and mitochondrial respiration. Heme is an essential nutrient, but its pro-oxidant nature may have toxic cellular effects if present at hi...

Full description

Bibliographic Details
Main Authors: Zhiqing Wang, Peng Zeng, Bing Zhou
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Biology
Subjects:
Online Access:https://doi.org/10.1186/s12915-022-01332-0