Identification and characterization of a heme exporter from the MRP family in Drosophila melanogaster
Abstract Background The heme group constitutes a major functional form of iron, which plays vital roles in various biological processes including oxygen transport and mitochondrial respiration. Heme is an essential nutrient, but its pro-oxidant nature may have toxic cellular effects if present at hi...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2022-06-01
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Series: | BMC Biology |
Subjects: | |
Online Access: | https://doi.org/10.1186/s12915-022-01332-0 |