Single-cell analysis of the cellular landscape of vulvar melanoma provides new insight for immunotherapy administration

Single-cell analysis of the cellular landscape of vulvar melanoma provides new insight for immunotherapy administration

Abstract Background Vulvar and vaginal melanoma (VuM & VaM) is a rare gynecologic malignancy with high mortality but low effectiveness to checkpoint immunotherapy compared to cutaneous melanoma. This article aims to elucidate the role of the disordered immune microenvironment in cancer progressi...

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Bibliographic Details
Main Authors: Xinqi Wang, Jiahui Li, Yifei Li, Mingyi Lv, Xue Dong, Zhenxin Fan, Tao Guo
Format: Article
Language:English
Published: BMC 2024-01-01
Series:BMC Cancer
Subjects:
Vulvar melanoma
scRNA-seq
Immune microenvironment
Immune cells; Case report
Online Access:https://doi.org/10.1186/s12885-024-11839-0

Internet

https://doi.org/10.1186/s12885-024-11839-0

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