SPINOPHILIN: A multiplayer tumor suppressor

SPINOPHILIN (SPN, PPP1R9B or NEURABIN-2) is a multifunctional protein that regulates protein–protein interactions in different cell signaling pathways. SPN is also one of the regulatory subunits of protein phosphatase 1 (PP1), implicated in the dephosphorylation of retinoblastoma protein (pRB) durin...

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Bibliographic Details
Main Authors: Eva M. Verdugo-Sivianes, Amancio Carnero
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2023-01-01
Series:Genes and Diseases
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352304222000150