An H3K9 methylation-dependent protein interaction regulates the non-enzymatic functions of a putative histone demethylase

An H3K9 methylation-dependent protein interaction regulates the non-enzymatic functions of a putative histone demethylase

H3K9 methylation (H3K9me) specifies the establishment and maintenance of transcriptionally silent epigenetic states or heterochromatin. The enzymatic erasure of histone modifications is widely assumed to be the primary mechanism that reverses epigenetic silencing. Here, we reveal an inversion of thi...

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Bibliographic Details
Main Authors: Gulzhan Raiymbek, Sojin An, Nidhi Khurana, Saarang Gopinath, Ajay Larkin, Saikat Biswas, Raymond C Trievel, Uhn-soo Cho, Kaushik Ragunathan
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-03-01
Series:eLife
Subjects:
heterochromatin
epigenetics
inheritance
biochemistry
demethylase
Online Access:https://elifesciences.org/articles/53155

Internet

https://elifesciences.org/articles/53155

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