Sulforaphane alleviates psoriasis by enhancing antioxidant defense through KEAP1-NRF2 Pathway activation and attenuating inflammatory signaling

Sulforaphane alleviates psoriasis by enhancing antioxidant defense through KEAP1-NRF2 Pathway activation and attenuating inflammatory signaling

Abstract Psoriasis is a chronic inflammatory skin disease that affects millions of people worldwide. Sulforaphane (SFN) has been shown to have anti-inflammatory and antioxidant properties. In this study, we investigated the effects of SFN on a mouse model of psoriasis induced by imiquimod (IMQ) and...

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Bibliographic Details
Main Authors: Chujun Ma, Chaode Gu, Panpan Lian, Junaid Wazir, Renwei Lu, Binjia Ruan, Lulu Wei, Li Li, Wenyuan Pu, Ziqi Peng, Wentong Wang, Yangyongyi Zong, Zhiqiang Huang, Hongwei Wang, Yan Lu, Zhonglan Su
Format: Article
Language:English
Published: Nature Publishing Group 2023-11-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06234-9

Internet

https://doi.org/10.1038/s41419-023-06234-9

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