Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway – an in vitro and in clinic study

Nasal irrigation with licorice extract (Glycyrrhiza glabra) in treating nasal polyps by reducing fibroblast differentiation and extracellular matrix production in TGF-β1-stimulated nasal polyp-derived fibroblasts by inhibiting the MAPK/ERK-1/2 pathway – an in vitro and in clinic study

Abstract Background To date, treating nasal polyps (NPs) is still a medical challenge. However, we have developed an innovative therapy using licorice extract (LE: Glycyrrhiza glabra) to treat rhinitis and sinusitis via nasal irrigation and have discovered that it significantly affects treatment of...

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Bibliographic Details
Main Authors: Geng-He Chang, Pei-Rung Yang, Yu-Ching Cheng, Ke-Hsin Hsu, Ching-Yuan Wu, Yao-Hsu Yang, Yu-Shih Lin, Cheng-Ming Hsu, Ming-Shao Tsai, Yao-Te Tsai, Pey-Jium Chang
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Complementary Medicine and Therapies
Subjects:
Licorice
Glycyrrhiza glabra
Nasal irrigation
Nasal polyp
Sinusitis
Fibroblast
Online Access:https://doi.org/10.1186/s12906-022-03791-y

Internet

https://doi.org/10.1186/s12906-022-03791-y

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