Translational Control by Ribosome Pausing in Bacteria: How a Non-uniform Pace of Translation Affects Protein Production and Folding

Protein homeostasis of bacterial cells is maintained by coordinated processes of protein production, folding, and degradation. Translational efficiency of a given mRNA depends on how often the ribosomes initiate synthesis of a new polypeptide and how quickly they read the coding sequence to produce...

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Autors principals: Ekaterina Samatova, Jan Daberger, Marija Liutkute, Marina V. Rodnina
Format: Article
Idioma:English
Publicat: Frontiers Media S.A. 2021-01-01
Col·lecció:Frontiers in Microbiology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fmicb.2020.619430/full