Detection of elevated levels of PINK1 in plasma from patients with idiopathic Parkinson’s disease

Detection of elevated levels of PINK1 in plasma from patients with idiopathic Parkinson’s disease

BackgroundsNumerous lines of evidence support the intricate interplay between Parkinson’s disease (PD) and the PINK1-dependent mitophagy process. This study aimed to evaluate differences in plasma PINK1 levels among idiopathic PD, PD syndromes (PDs), and healthy controls.MethodsA total of 354 partic...

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Bibliographic Details
Main Authors: Xianchai Hong, Yi Zheng, Jialong Hou, Tao Jiang, Yao Lu, Wenwen Wang, Shuoting Zhou, Qianqian Ye, Chenglong Xie, Jia Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-04-01
Series:Frontiers in Aging Neuroscience
Subjects:
PINK1
α-synuclein oligomer
biomarkers
mitophagy
Parkinson’s disease
Online Access:https://www.frontiersin.org/articles/10.3389/fnagi.2024.1369014/full

Internet

https://www.frontiersin.org/articles/10.3389/fnagi.2024.1369014/full

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