Facilitating Drug Discovery in Breast Cancer by Virtually Screening Patients Using In Vitro Drug Response Modeling

Facilitating Drug Discovery in Breast Cancer by Virtually Screening Patients Using In Vitro Drug Response Modeling

(1) Background: Drug imputation methods often aim to translate in vitro drug response to in vivo drug efficacy predictions. While commonly used in retrospective analyses, our aim is to investigate the use of drug prediction methods for the generation of novel drug discovery hypotheses. Triple-negati...

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Bibliographic Details
Main Authors: Robert F. Gruener, Alexander Ling, Ya-Fang Chang, Gladys Morrison, Paul Geeleher, Geoffrey L. Greene, R. Stephanie Huang
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:Cancers
Subjects:
transcriptome
drug discovery
breast cancer
Wee1
drug imputation
Online Access:https://www.mdpi.com/2072-6694/13/4/885

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https://www.mdpi.com/2072-6694/13/4/885

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