Role of succinate in airway epithelial cell regulation following traumatic lung injury

Role of succinate in airway epithelial cell regulation following traumatic lung injury

Lung contusion and gastric aspiration (LC and GA) are major risk factors for developing acute respiratory distress following trauma. Hypoxia from lung injury is mainly regulated by hypoxia-inducible factor 1α (HIF-1α). Published data from our group indicate that HIF-1α regulation in airway epithelia...

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Bibliographic Details
Main Authors: Madathilparambil V. Suresh, Sinan Aktay, George Yalamanchili, Sumeet Solanki, Dily Thazhath Sathyarajan, Manikanta Swamy Arnipalli, Subramaniam Pennathur, Krishnan Raghavendran
Format: Article
Language:English
Published: American Society for Clinical investigation 2023-09-01
Series:JCI Insight
Subjects:
Inflammation
Pulmonology
Online Access:https://doi.org/10.1172/jci.insight.166860

Internet

https://doi.org/10.1172/jci.insight.166860

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