Antimycobacterial Activities of N-Substituted-Glycinyl 1H-1,2,3-Triazolyl Oxazolidinones and Analytical Method Development and Validation for a Representative Compound

Antimycobacterial Activities of N-Substituted-Glycinyl 1H-1,2,3-Triazolyl Oxazolidinones and Analytical Method Development and Validation for a Representative Compound

Twelve N-substituted-glycinyl triazolyl oxazolidinone derivatives were screened for antimycobacterial activity against susceptible (Mycobacterium tuberculosis (Mtb) H37Rv) and resistant (isoniazid (INH)-resistant Mtb (SRI 1369), rifampin (RMP)-resistant Mtb (SRI 1367), and ofloxacin (OFX)-resistant...

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Bibliographic Details
Main Authors: Naser F. Al-Tannak, Oludotun A. Phillips
Format: Article
Language:English
Published: MDPI AG 2017-10-01
Series:Scientia Pharmaceutica
Subjects:
antimycobacterial activity
linezolid
PH-189
substituted-glycinyl triazolyl-oxazolidinone
quadrupole-time of flight mass spectrometry
ultraHigh Performance Liquid Chromatography
Online Access:https://www.mdpi.com/2218-0532/85/4/34

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https://www.mdpi.com/2218-0532/85/4/34

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