A parapoxviral virion protein inhibits NF-κB signaling early in infection.

A parapoxviral virion protein inhibits NF-κB signaling early in infection.

Poxviruses have evolved unique proteins and mechanisms to counteract the nuclear factor κB (NF-κB) signaling pathway, which is an essential regulatory pathway of host innate immune responses. Here, we describe a NF-κB inhibitory virion protein of orf virus (ORFV), ORFV073, which functions very early...

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Bibliographic Details
Main Authors: Sushil Khatiwada, Gustavo Delhon, Ponnuraj Nagendraprabhu, Sabal Chaulagain, Shuhong Luo, Diego G Diel, Eduardo F Flores, Daniel L Rock
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-08-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006561

Internet

https://doi.org/10.1371/journal.ppat.1006561

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