Identification of a natural antagonist for signal transducer and activator of transcription 3 (STAT3) by computational approach

Identification of a natural antagonist for signal transducer and activator of transcription 3 (STAT3) by computational approach

The transcription factor family includes the cluster protein signal transducer and activator of transcription 3 (STAT3). Colorectal cancer (CRC) is predisposed to develop and spread when STAT 3 is abnormally activated because it speeds up cell division, prevents differentiation, and suppresses apopt...

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Bibliographic Details
Main Authors: Syeda Mobeen Anjum, Katari Sudheer Kumar, Amineni Umamaheswari, Dinesh Lakhanpal, Sandeep Swargam, Khateef Riazunnisa, Thummala Chandrasekhar
Format: Article
Language:English
Published: Elsevier 2023-01-01
Series:Results in Chemistry
Subjects:
STAT3
CRC
Glide
Docking
MD simulations
Online Access:http://www.sciencedirect.com/science/article/pii/S2211715623002096

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http://www.sciencedirect.com/science/article/pii/S2211715623002096

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