Development of an ancestral DC and TLR4-inducing multi-epitope peptide vaccine against the spike protein of SARS-CoV and SARS-CoV-2 using the advanced immunoinformatics approaches

Development of an ancestral DC and TLR4-inducing multi-epitope peptide vaccine against the spike protein of SARS-CoV and SARS-CoV-2 using the advanced immunoinformatics approaches

The oldest human coronavirus that started pandemics is severe acute respiratory syndrome virus (SARS-CoV). While SARS-CoV was eradicated, its new version, SARS-CoV2, caused the global pandemic of COVID-19. Evidence highlights the harmful events orchestrated by these viruses are mediated by Spike (S)...

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Bibliographic Details
Main Authors: Cena Aram, Parsa Alijanizadeh, Kiarash Saleki, Leila Karami
Format: Article
Language:English
Published: Elsevier 2024-09-01
Series:Biochemistry and Biophysics Reports
Subjects:
Immunoinformatics
Multi-epitope
SARS-CoV
Reverse vaccinology
SARS-CoV-2
Computational immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2405580824001092

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http://www.sciencedirect.com/science/article/pii/S2405580824001092

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