Gene Profiling of a 3D Psoriatic Skin Model Enriched in T Cells: Downregulation of <i>PTPRM</i> Promotes Keratinocyte Proliferation through Excessive ERK1/2 Signaling
Psoriasis is a complex, immune-mediated skin disease involving a wide range of epithelial and immune cells. The underlying mechanisms that govern the epidermal defects and immunological dysfunction observed in this condition remain largely unknown. In recent years, the emergence of new, more sophist...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2022-09-01
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| Series: | Cells |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2073-4409/11/18/2904 |