Intravitreal injection of peptides PnPa11 and PnPa13, derivatives of Phoneutria nigriventer spider venom, prevents retinal damage

Intravitreal injection of peptides PnPa11 and PnPa13, derivatives of Phoneutria nigriventer spider venom, prevents retinal damage

Abstract Background: PnPa11 and PnPa13 are synthetic peptides derived from Phoneutria nigriventer spider venom, which display antinociceptive and neuroprotective properties. In this work, we evaluated the safety of intravitreal use and the neuroprotective effect of these peptides. Methods: The cyt...

Full description

Bibliographic Details
Main Authors: Lays Fernanda Nunes Dourado, Flavia Rodrigues da Silva, Cibele Rodrigues Toledo, Carolina Nunes da Silva, Cleildo Pereira Santana, Bruna Lopes da Costa, Maria Elena de Lima, Armando da Silva Cunha Junior
Format: Article
Language:English
Published: SciELO
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
Phoneutria nigriventer
Neuroprotection
Retinal diseases
Toxicity
Blue LED
Synthetic peptides
Online Access:http://www.scielo.br/pdf/jvatitd/v26/1678-9199-jvatitd-26-e20200031.pdf

Internet

http://www.scielo.br/pdf/jvatitd/v26/1678-9199-jvatitd-26-e20200031.pdf

Similar Items