DNA and RNA oxidative damage in the retina is associated with ganglion cell mitochondria
Abstract This study examines retinas from a rat glaucoma model for oxidized nucleosides 8OHdG and 8OHG, biomarkers for oxidative damage of DNA and RNA, respectively. Immunohistochemical data indicate a predominant localization of 8OHdG/8OHG in retinal ganglion cells (RGCs). The levels for these oxid...
| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | English |
| Publicado: |
Nature Portfolio
2022-05-01
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| Series: | Scientific Reports |
| Acceso en liña: | https://doi.org/10.1038/s41598-022-12770-9 |