Efficacy of dapagliflozin in the treatment of HFrEF with obstructive sleep apnea syndrome (DAHOS study): study protocol for a multicentric, prospective, randomized controlled clinical trial

Abstract Background Heart failure with reduced ejection fraction (HFrEF) is associated with sleep dyspnea (SDB), which plays an adverse role in the pathophysiology of the condition. SDB management in HFrEF, however, remains controversial. HFrEF’s medical management has recently made significant prog...

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Bibliographic Details
Main Authors: Liang Xie, Songsong Song, Shengnan Li, Qin Wei, Hong Liu, Chao Zhao, Fuchao Yu, Jiayi Tong
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Trials
Subjects:
Online Access:https://doi.org/10.1186/s13063-023-07332-x