Synthesis, Molecular Docking and Anticancer Activity of Diflunisal Derivatives as Cyclooxygenase Enzyme Inhibitors

Cyclooxygenase enzymes play a vital role in inflammatory pathways in the human body. Apart from their relation with inflammation, the additional involvement of COX-2 enzyme with cancer activity was recently discovered. In some cancer types the level of COX-2 enzyme is increased indicating that this...

Full description

Bibliographic Details
Main Authors: Göknil Pelin Coşkun, Teodora Djikic, Taha Bartu Hayal, Nezaket Türkel, Kemal Yelekçi, Fikrettin Şahin, Ş. Güniz Küçükgüzel
Format: Article
Language:English
Published: MDPI AG 2018-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/8/1969