Utilization of RESOLV with polymer to produce prazosin hydrochloride nanoparticles and optimization of the process parameters

Utilization of RESOLV with polymer to produce prazosin hydrochloride nanoparticles and optimization of the process parameters

Abstract In this study, rapid expansion of a supercritical solution into a Liquid Solvent (RESOLV) was used for the first time to produce pharmaceutical nanoparticles of Prazosin hydrochloride (PRH). The Taguchi method (robust design) was utilized to design the experiments and ensure obtaining the o...

Full description

Bibliographic Details
Main Authors: Eslam Ansari, Bizhan Honarvar, Seyed Ali Sajadian, Zahra Arab Aboosadi, Mehdi Azizi
Format: Article
Language:English
Published: Nature Portfolio 2024-08-01
Series:Scientific Reports
Subjects:
Prazosin hydrochloride
RESOLV
Optimization
Taguchi
Polyvinyl pyrrolidone
Online Access:https://doi.org/10.1038/s41598-024-69128-6

Internet

https://doi.org/10.1038/s41598-024-69128-6

Similar Items