LDH as an adjuvant makes Brucella outer-membrane vesicles and outer-membrane vesicle-associated proteins highly protective in mice

Objective(s): Existing Brucella vaccines are attenuated and can cause vaccine-associated brucellosis; and these safety concerns have affected their application. Although subunit vaccines have the advantages of safety, efficacy, low cost, and rapid production, they are usually poorly immunogenic and...

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Bibliographic Details
Main Authors: Xiaoyu Deng, Jinke He, Jinfeng Xu, Yueli Wang, Jihai Yi, Huan Zhang, Yong Wang, Zhen Wang, Chuangfu Chen
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-05-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_21876_e398bdff729076b26ca9c73e82b3c0e2.pdf