An in vitro model of cancer invasion with heterogeneous ECM created with droplet microfluidics

Metastasis is a multi-step process that is critically affected by cues from the tumor micro-environment (TME), such as from the extracellular matrix (ECM). The role of the ECM in the onset of metastasis, invasion, is not yet fully understood. A further complicating factor is that the ECM in the TME...

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Bibliographic Details
Main Authors: Mohammad Jouybar, Jelle J. F. Sleeboom, Elnaz Vaezzadeh, Cecilia M. Sahlgren, Jaap M. J. den Toonder
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-11-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1267021/full