An in vitro model of cancer invasion with heterogeneous ECM created with droplet microfluidics
Metastasis is a multi-step process that is critically affected by cues from the tumor micro-environment (TME), such as from the extracellular matrix (ECM). The role of the ECM in the onset of metastasis, invasion, is not yet fully understood. A further complicating factor is that the ECM in the TME...
Main Authors: | Mohammad Jouybar, Jelle J. F. Sleeboom, Elnaz Vaezzadeh, Cecilia M. Sahlgren, Jaap M. J. den Toonder |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-11-01
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Series: | Frontiers in Bioengineering and Biotechnology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fbioe.2023.1267021/full |
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