Broadly Effective ACE2 Decoy Proteins Protect Mice from Lethal SARS-CoV-2 Infection

Broadly Effective ACE2 Decoy Proteins Protect Mice from Lethal SARS-CoV-2 Infection

ABSTRACT As severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants have been causing increasingly serious drug resistance problem, development of broadly effective and hard-to-escape anti-SARS-CoV-2 agents is an urgent need. Here, we describe further development and characterization o...

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Bibliographic Details
Main Authors: Mengjia Lu, Weitong Yao, Yujun Li, Danting Ma, Zhaoyong Zhang, Haimin Wang, Xiaojuan Tang, Yanqun Wang, Chao Li, Dechun Cheng, Hua Lin, Yandong Yin, Jincun Zhao, Guocai Zhong
Format: Article
Language:English
Published: American Society for Microbiology 2023-08-01
Series:Microbiology Spectrum
Subjects:
SARS-CoV-2
variant of concern
Omicron
ACE2
receptor decoy
ACE2-Ig
Online Access:https://journals.asm.org/doi/10.1128/spectrum.01100-23

Internet

https://journals.asm.org/doi/10.1128/spectrum.01100-23

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