Investigation of the causal relationship between ALS and autoimmune disorders: a Mendelian randomization study

Investigation of the causal relationship between ALS and autoimmune disorders: a Mendelian randomization study

Abstract Background Epidemiological studies have reported an association between amyotrophic lateral sclerosis (ALS) and different autoimmune disorders. This study aims to explore the causal relationship between autoimmune disorders and ALS using Mendelian randomization (MR). Methods To test the gen...

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Bibliographic Details
Main Authors: Paria Alipour, Konstantin Senkevich, Jay P. Ross, Dan Spiegelman, Despoina Manousaki, Patrick A. Dion, Guy A. Rouleau
Format: Article
Language:English
Published: BMC 2022-11-01
Series:BMC Medicine
Subjects:
Mendelian randomization
Amyotrophic lateral sclerosis
Autoimmune disorders
Causal relationship
Online Access:https://doi.org/10.1186/s12916-022-02578-9

Internet

https://doi.org/10.1186/s12916-022-02578-9

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