Structural basis of death domain signaling in the p75 neurotrophin receptor

Structural basis of death domain signaling in the p75 neurotrophin receptor

Death domains (DDs) mediate assembly of oligomeric complexes for activation of downstream signaling pathways through incompletely understood mechanisms. Here we report structures of complexes formed by the DD of p75 neurotrophin receptor (p75NTR) with RhoGDI, for activation of the RhoA pathway, with...

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Bibliographic Details
Main Authors: Zhi Lin, Jason Y Tann, Eddy TH Goh, Claire Kelly, Kim Buay Lim, Jian Fang Gao, Carlos F Ibanez
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-12-01
Series:eLife
Subjects:
p75
nmr
structure
binding
receptor
Online Access:https://elifesciences.org/articles/11692

Internet

https://elifesciences.org/articles/11692

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