A general lack of compensation for gene dosage in yeast

Abstract Gene copy number variation has been discovered in humans, between related species, and in different cancer tissues, but it is unclear how much of this genomic‐level variation leads to changes in the level of protein abundance. To address this, we eliminated one of the two genomic copies of...

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Bibliographic Details
Main Authors: Michael Springer, Jonathan S Weissman, Marc W Kirschner
Format: Article
Language:English
Published: Springer Nature 2010-05-01
Series:Molecular Systems Biology
Subjects:
Online Access:https://doi.org/10.1038/msb.2010.19