A general lack of compensation for gene dosage in yeast
Abstract Gene copy number variation has been discovered in humans, between related species, and in different cancer tissues, but it is unclear how much of this genomic‐level variation leads to changes in the level of protein abundance. To address this, we eliminated one of the two genomic copies of...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Springer Nature
2010-05-01
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Series: | Molecular Systems Biology |
Subjects: | |
Online Access: | https://doi.org/10.1038/msb.2010.19 |