Propranolol Relieves L-Dopa-Induced Dyskinesia in Parkinsonian Mice

Propranolol Relieves L-Dopa-Induced Dyskinesia in Parkinsonian Mice

Background: Parkinsonism is caused by dopamine (DA) insufficiency and results in a hypokinetic movement disorder. Treatment with L-Dopa can restore DA availability and improve motor function, but patients can develop L-Dopa-induced dyskinesia (LID), a secondary hyperkinetic movement disorder. The me...

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Bibliographic Details
Main Authors: Ziqing Shi, Ian J. Bamford, Jonathan W. McKinley, Suma Priya Sudarsana Devi, Annie Vahedipour, Nigel S. Bamford
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Brain Sciences
Subjects:
Parkinson’s disease
striatum
acetylcholine
cholinergic
interneuron
β-adrenergic
Online Access:https://www.mdpi.com/2076-3425/10/12/903

Internet

https://www.mdpi.com/2076-3425/10/12/903

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