Non‐genetic heterogeneity, altered cell fate and differentiation therapy

Abstract Altered capacity for self‐renewal and differentiation is a hallmark of cancer, and many tumors are composed of cells with a developmentally immature phenotype. Among the malignancies where processes that govern cell fate decisions have been studied most extensively is acute myeloid leukemia...

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Bibliographic Details
Main Authors: Alexander C Lewis, Lev M Kats
Format: Article
Language:English
Published: Springer Nature 2021-03-01
Series:EMBO Molecular Medicine
Subjects:
Online Access:https://doi.org/10.15252/emmm.202012670