A molecularly cloned, live-attenuated japanese encephalitis vaccine SA14-14-2 virus: a conserved single amino acid in the ij Hairpin of the Viral E glycoprotein determines neurovirulence in mice.

A molecularly cloned, live-attenuated japanese encephalitis vaccine SA14-14-2 virus: a conserved single amino acid in the ij Hairpin of the Viral E glycoprotein determines neurovirulence in mice.

Japanese encephalitis virus (JEV), a mosquito-borne flavivirus that causes fatal neurological disease in humans, is one of the most important emerging pathogens of public health significance. JEV represents the JE serogroup, which also includes West Nile, Murray Valley encephalitis, and St. Louis en...

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Bibliographic Details
Main Authors: Sang-Im Yun, Byung-Hak Song, Jin-Kyoung Kim, Gil-Nam Yun, Eun-Young Lee, Long Li, Richard J Kuhn, Michael G Rossmann, John D Morrey, Young-Min Lee
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC4117607?pdf=render

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http://europepmc.org/articles/PMC4117607?pdf=render

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