Enhanced Store-Operated Calcium Entry in Platelets is Associated with Peripheral Artery Disease in Type 2 Diabetes

Enhanced Store-Operated Calcium Entry in Platelets is Associated with Peripheral Artery Disease in Type 2 Diabetes

Background/Aims: Platelet dysfunction plays an important role in thrombosis in diabetes with peripheral artery disease (PAD). Store-operated calcium entry (SOCE) and stromal interaction molecule 1 (STIM1) regulate platelet activity by modulating calcium influx. We hypothesized that enhanced SOCE in...

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Bibliographic Details
Main Authors: Weijie Xia, Yingsha Li, Bin Wang, Jing Chen, Xiaojing Wang, Qianqian Sun, Fang Sun, Zhiyong Li, Zhigang Zhao
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-11-01
Series:Cellular Physiology and Biochemistry
Subjects:
Peripheral artery disease
Type 2 diabetes
Platelets
Store-operated calcium entry
Online Access:http://www.karger.com/Article/FullText/438555

Internet

http://www.karger.com/Article/FullText/438555

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