Inhibition of miR-4640-5p alleviates pulmonary hypertension in chronic obstructive pulmonary disease patients by regulating nitric oxide synthase 1

Abstract Background Pulmonary hypertension (PH) is a devastating disease characterized by vasoconstriction and vascular remodeling, leading to right ventricular failure and death. PH is a common complication of chronic obstructive pulmonary disease (COPD). Accumulating evidence demonstrate that micr...

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Bibliographic Details
Main Authors: Zhao Yang, Ping Li, Qun Yuan, Xi Wang, Hong-Hong Ma, Bing Zhuan
Format: Article
Language:English
Published: BMC 2023-03-01
Series:Respiratory Research
Subjects:
Online Access:https://doi.org/10.1186/s12931-023-02387-5