Recapitulation of cell-like KRAS4b membrane dynamics on complex biomimetic membranes

Summary: Understanding the spatiotemporal distribution and dynamics of RAS on the plasma membrane (PM) is the key for elucidating the molecular mechanisms of the RAS signaling pathway. Single particle tracking (SPT) experiments show that in cells, KRAS diffuses in at least three interchanging states...

Full description

Bibliographic Details
Main Authors: Rebika Shrestha, De Chen, Peter Frank, Dwight V. Nissley, Thomas J. Turbyville
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:iScience
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004221015789