The effect of induced hyperammonaemia on sleep and melanopsin-mediated pupillary light response in patients with liver cirrhosis: A single-blinded randomized crossover trial.

The effect of induced hyperammonaemia on sleep and melanopsin-mediated pupillary light response in patients with liver cirrhosis: A single-blinded randomized crossover trial.

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<h4>Background & aims</h4>Sleep disturbances are related to hepatic encephalopathy and hyperammonaemia in patients with cirrhosis. The circadian rhythm is regulated by light stimulation of the retina via melanopsin-containing ganglion cells. The study aimed to investigate whether ind...

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Bibliographic Details
Main Authors: Anna Emilie Kann, Shakoor Ba-Ali, Jakob B Seidelin, Fin Stolze Larsen, Steffen Hamann, Peter Nissen Bjerring
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0275067

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https://doi.org/10.1371/journal.pone.0275067

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