NF-κB regulates mesenchymal transition for the induction of non-small cell lung cancer initiating cells.

NF-κB regulates mesenchymal transition for the induction of non-small cell lung cancer initiating cells.

The epithelial-to-mesenchymal transition (EMT) is a de-differentiation process that has been implicated in metastasis and the generation of cancer initiating cells (CICs) in solid tumors. To examine EMT in non-small cell lung cancer (NSCLC), we utilized a three dimensional (3D) cell culture system i...

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Bibliographic Details
Main Authors: Manish Kumar, David F Allison, Natalya N Baranova, J Jacob Wamsley, Adam J Katz, Stefan Bekiranov, David R Jones, Marty W Mayo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3728367?pdf=render

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http://europepmc.org/articles/PMC3728367?pdf=render

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