AKT inhibitor Hu7691 induces differentiation of neuroblastoma cells

AKT inhibitor Hu7691 induces differentiation of neuroblastoma cells

While neuroblastoma accounts for 15% of childhood tumor-related deaths, treatments against neuroblastoma remain scarce and mainly consist of cytotoxic chemotherapeutic drugs. Currently, maintenance therapy of differentiation induction is the standard of care for neuroblastoma patients in clinical, e...

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Bibliographic Details
Main Authors: Shaowei Bing, Senfeng Xiang, Zhimei Xia, Yilong Wang, Zhonghai Guan, Jinxin Che, Aixiao Xu, Xiaowu Dong, Ji Cao, Bo Yang, Jinhu Wang, Qiaojun He, Meidan Ying
Format: Article
Language:English
Published: Elsevier 2023-04-01
Series:Acta Pharmaceutica Sinica B
Subjects:
Neuroblastoma
Differentiation therapy
High-risk
AKT
AKT inhibitor
Target therapy
Online Access:http://www.sciencedirect.com/science/article/pii/S2211383523000266

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http://www.sciencedirect.com/science/article/pii/S2211383523000266

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