The FUR-like regulators PerRA and PerRB integrate a complex regulatory network that promotes mammalian host-adaptation and virulence of Leptospira interrogans.

Leptospira interrogans, the causative agent of most cases of human leptospirosis, must respond to myriad environmental signals during its free-living and pathogenic lifestyles. Previously, we compared L. interrogans cultivated in vitro and in vivo using a dialysis membrane chamber (DMC) peritoneal i...

Full description

Bibliographic Details
Main Authors: André A Grassmann, Crispin Zavala-Alvarado, Everton B Bettin, Mathieu Picardeau, Nadia Benaroudj, Melissa J Caimano
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1009078