In vitro characterization of Haemonchus contortus trehalose-6-phosphate phosphatase and its immunomodulatory effects on peripheral blood mononuclear cells (PBMCs)

In vitro characterization of Haemonchus contortus trehalose-6-phosphate phosphatase and its immunomodulatory effects on peripheral blood mononuclear cells (PBMCs)

Abstract Background Trehalose-6-phosphate phosphatase (TPP6) is a key enzyme in the trehalose biosynthesis pathway. The accumulation of TPP6 inside the body is harmful to the pathogen, but almost nothing is currently known about the function of TPP6 from Haemonchus contortus (CRE-GOB-1). Methods The...

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Bibliographic Details
Main Authors: ZhaoHai Wen, XinRan Xie, Muhammad Tahir Aleem, Kalibixiati Aimulajiang, Cheng Chen, Meng Liang, XiaoKai Song, LiXin Xu, XiangRui Li, RuoFeng Yan
Format: Article
Language:English
Published: BMC 2021-12-01
Series:Parasites & Vectors
Subjects:
Haemonchus contortus
Trehalose-6-phosphate phosphatase
PBMCs
Immunomodulation
Online Access:https://doi.org/10.1186/s13071-021-05115-4

Internet

https://doi.org/10.1186/s13071-021-05115-4

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