Interleukin Variants Are Associated with the Development and Progression of IgA Nephropathy: A Candidate-Gene Association Study and Meta-Analysis

Interleukin Variants Are Associated with the Development and Progression of IgA Nephropathy: A Candidate-Gene Association Study and Meta-Analysis

The interleukin-1 gene cluster encodes cytokines, which modulate mesangial cell proliferation and matrix expansion, both constituting central factors in the development and progression of immunoglobulin A nephropathy (IgAN). A candidate-gene study was performed to examine the association of polymorp...

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Bibliographic Details
Main Authors: Ioanna Chronopoulou, Maria Tziastoudi, Georgios Pissas, Efthimios Dardiotis, Maria Dardioti, Spyridon Golfinopoulos, Georgios Filippidis, Peter R. Mertens, Evangelia E. Tsironi, Vassilios Liakopoulos, Theodoros Eleftheriadis, Ioannis Stefanidis
Format: Article
Language:English
Published: MDPI AG 2023-11-01
Series:International Journal of Molecular Sciences
Subjects:
gene polymorphism
immunoglobulin A nephropathy
interleukin-1α
<i>IL1A</i>
interleukin-1β
<i>IL1B</i>
Online Access:https://www.mdpi.com/1422-0067/24/22/16347

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https://www.mdpi.com/1422-0067/24/22/16347

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