Defining synphenotype groups in Xenopus tropicalis by use of antisense morpholino oligonucleotides.

To identify novel genes involved in early development, and as proof-of-principle of a large-scale reverse genetics approach in a vertebrate embryo, we have carried out an antisense morpholino oligonucleotide (MO) screen in Xenopus tropicalis, in the course of which we have targeted 202 genes express...

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Bibliographic Details
Main Authors: Amer Ahmed Rana, Clara Collart, Michael J Gilchrist, J C Smith
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2006-11-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC1636699?pdf=render