Demethylase ALKBH5 suppresses invasion of gastric cancer via PKMYT1 m6A modification

Demethylase ALKBH5 suppresses invasion of gastric cancer via PKMYT1 m6A modification

Abstract Background Gastric cancer (GC) is one of the most pernicious tumors that seriously harm human healthcare. GC metastasis is one of the prime cause of failed cancer treatment, but correlation between N6-methyladenosine (m6A) and GC metastasis was less reported. Methods Methylated RNA immunopr...

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Bibliographic Details
Main Authors: Yiyang Hu, Chunli Gong, Zhibin Li, Jiao Liu, Yang Chen, Yu Huang, Qiang Luo, Sumin Wang, Yu Hou, Shiming Yang, Yufeng Xiao
Format: Article
Language:English
Published: BMC 2022-02-01
Series:Molecular Cancer
Subjects:
ALKBH5
Invasion
Metastasis
Demethylase activity
PKMYT1
Gastric cancer
Online Access:https://doi.org/10.1186/s12943-022-01522-y

Internet

https://doi.org/10.1186/s12943-022-01522-y

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