Efficiency of treatment of laryngopharyngeal reflux with proton pump inhibitors depending on the <i>CYP2C19</i> polymorphism

Introduction. A treatment for LFR for many years, the superiority of PPIs over placebos is still controversial. Of particular clinical importance is the metabolic rate of PPIs in hepatocytes using the cytochrome P450 system with the participation of the isoenzyme CYP2C19 and partially CYP3A4Аim. We...

Full description

Bibliographic Details
Main Authors: I. B. Angotoeva, N. P. Denisenko, D. A. Sychev, E. V. Schepkina, M. M. Magomedova
Format: Article
Language:Russian
Published: Remedium Group LLC 2022-01-01
Series:Медицинский совет
Subjects:
Online Access:https://www.med-sovet.pro/jour/article/view/6632