Nuclear Actin Polymerized by mDia2 Confines Centromere Movement during CENP-A Loading

Summary: Centromeres are specialized chromosomal regions epigenetically defined by the histone H3 variant centromere protein A (CENP-A). CENP-A needs to be replenished in every cell cycle, but how new CENP-A is stably incorporated into centromeric chromatin remains unclear. We have discovered that a...

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Bibliographic Details
Main Authors: Chenshu Liu, Ruijun Zhu, Yinghui Mao
Format: Article
Language:English
Published: Elsevier 2018-11-01
Series:iScience
Online Access:http://www.sciencedirect.com/science/article/pii/S2589004218301901