Heterologous (Over) Expression of Human SoLute Carrier (SLC) in Yeast: A Well-Recognized Tool for Human Transporter Function/Structure Studies

For more than 20 years, yeast has been a widely used system for the expression of human membrane transporters. Among them, more than 400 are members of the largest transporter family, the SLC superfamily. SLCs play critical roles in maintaining cellular homeostasis by transporting nutrients, ions, a...

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Bibliographic Details
Main Authors: Lorena Pochini, Michele Galluccio
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/8/1206