Plasmid-mediated mcr-1 colistin resistance in Escherichia coli and Klebsiella spp. clinical isolates from the Western Cape region of South Africa

Plasmid-mediated mcr-1 colistin resistance in Escherichia coli and Klebsiella spp. clinical isolates from the Western Cape region of South Africa

Abstract Background Colistin is a last resort antibiotic for the treatment of carbapenem-resistant Gram negative infections. Until recently, mechanisms of colistin resistance were limited to chromosomal mutations which confer a high fitness cost and cannot be transferred between organisms. However,...

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Bibliographic Details
Main Authors: Mae Newton-Foot, Yolandi Snyman, Motlatji Reratilwe Bonnie Maloba, Andrew Christopher Whitelaw
Format: Article
Language:English
Published: BMC 2017-08-01
Series:Antimicrobial Resistance and Infection Control
Subjects:
Colistin resistance
mcr-1
plasmid-mediated resistance
E. coli
Klebsiella spp
South Africa
Online Access:http://link.springer.com/article/10.1186/s13756-017-0234-8

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http://link.springer.com/article/10.1186/s13756-017-0234-8

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