Roles of epidermal growth factor receptor, claudin-1 and occludin in multi-step entry of hepatitis C virus into polarized hepatoma spheroids.

The multi-step process of hepatitis C virus (HCV) entry is facilitated by various host factors, including epidermal growth factor receptor (EGFR) and the tight junction proteins claudin-1 (CLDN1) and occludin (OCLN), which are thought to function at later stages of the HCV entry process. Using singl...

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Bibliographic Details
Main Authors: Chui-Wa So, Marion Sourisseau, Shamila Sarwar, Matthew J Evans, Glenn Randall
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-12-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1011887